Biomarkers of Kidney Failure: A Brief Review (Article 356: .5 Clock Hour) (Report) by Journal of Continuing Education Topics & Issues

Biomarkers of Kidney Failure: A Brief Review (Article 356: .5 Clock Hour) (Report)

By Journal of Continuing Education Topics & Issues

  • Release Date: 2009-08-01
  • Category: Education

Brief Description

As the population in the United States continues to age, the number of patients with chronic kidney disease (CKD) has dramatically increased. CKD, a reduction in the glomerular filtration rate (GFR), is increasing, in part because of the aging population as well as the greater prevalence of obesity and hypertension. Because GFR declines 1% per year for every year of life after the third decade, living longer means that it is possible to outlive one's renal function and to require renal replacement therapy to stay alive. In addition, this longevity increases the risk of developing diseases such as diabetes, hypertension, and coronary artery disease, all of which have direct adverse effects on kidney function. A longer life also increases the risk of exposure to nephrotoxic medications for other health conditions such as arthritis (nonsteroidal anti-inflammatory drugs [NSAIDs]), infections (antibiotics), cancer (chemotherapy), gastroesophageal reflux disease (proton pump inhibitors), and coronary artery disease (radiocontrast agents). The reported incidence of acute renal failure (ARF) in hospitalized patients is 4-7% and constitutes 1% of all hospitalizations. Creatinine and Creatinine Clearance as a Marker of Renal Function

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